International Journal of Behavioral Nutrition and Physical Activity
Top medRxiv preprints most likely to be published in this journal, ranked by match strength.
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This study compared the effects of a 25-min nap opportunity and a 10-min non-sleep deep rest (NSDR) condition on perceptual, cognitive, and physical performance in physically active young adults. Sixty participants (26 female, 34 male; 22 {+/-} 4 years) were randomly assigned to one of three groups (nap, NSDR, control; n = 20 each). All groups completed identical assessments immediately, 20 min, and 40 min post-intervention. Mixed-effects models, adjusted for sex, prior-night sleep, and weekly p...
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BackgroundPacked lunches are a common feature of early childhood food provision, yet evidence describing their nutritional composition in early years settings remains limited. Understanding the foods provided during this developmental period is important, given the potential influence of early dietary exposures on later health. AimTo characterise the composition, nutritional quality, cost, and dietary patterns of packed lunches brought from home in Early Childhood Education and Care settings, a...
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BackgroundPhysical activity is a key modifiable determinant of health, yet current guidelines primarily emphasize moderate-to-vigorous physical activity and provide limited guidance on other actionable dimensions such as daily step count and sedentary time. The growing availability of wearables enables high-resolution measurement of these metrics and assessment of their associations with clinical outcomes. MethodsMinute-level wearable data from adult participants of All of Us between 2015-2023 ...
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BackgroundEvidence on how leisure-time physical activity (LTPA) improves lifetime body mass index (BMI) remains fragmented and prone to confounding. MethodsWe pooled 14,993 adults (30-90 y; 52.7% women; cohorts: REGICOR-ACRISC, ILERVAS, ARTPER) with baseline estimated LTPA (moderate-to-vigorous LTPA [MVLTPA] in REGICOR-ACRISC), genotype, and repeated BMI values from electronic health records (1990-2024, 36,157 measures). LTPA was categorized into cohort-specific quartiles; MVLTPA in 0, <100, <2...
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BackgroundOverweight and obesity are causing growing public health, economic and clinical burden, particularly within under-resourced communities. There is an urgent need to develop an in-depth understanding of experiences of weight management, and preferences for support within under-resourced communities, with a view to developing more effective weight management interventions. MethodsFocus groups were run in under-resourced communities using storyboarding; a method to facilitate inclusive co...
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Outcomes from the COSMOS trial have reinforced the notion of flavanols as important plant-derived bioactives contributing to cardiovascular health. As discussions continue on whether specific dietary reference values for flavanols are warranted, it is possible that existing dietary guidelines emphasizing fruits and vegetables already yield sufficient flavanol intake levels. If this were the case, developing flavanol specific dietary reference values might be unnecessary. This study therefore aim...
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IntroductionMechanistic research has shown that prior obesity induces durable transcriptomic and epigenetic reprogramming in adipose tissue that persists after weight loss and predisposes individuals to weight regain. This phenomenon, termed obesogenic memory (OM), is currently conceptualized primarily as a molecular process. We propose extending OM beyond adipose tissue biology to include interacting biological and sociocultural processes through which past exposures shape present physiological...
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BackgroundFood systems--particularly livestock production--account for substantial greenhouse gas (GHG) emissions, while unhealthy diets, characterized by excessive animal-based and insufficient plant-based food consumption, are a major risk factor for all-cause mortality in Europe. Implementing climate mitigation policies related to the GHG emissions of the food system could therefore bring important health co-benefits. MethodsWe developed a health impact assessment model based on a life table...
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The ubiquitous use of digital tools may be beneficial for improving physical activity across diverse populations. It remains unknown however, how publicly available, cost-free physical activity apps adhere to behaviour change techniques, and how users rate these apps. To explore the number of publicly available physical activity apps and relationships among behaviour science techniques, subjective quality, and user ratings. Exploratory content analysis of 17 apps meeting inclusion criteria. The ...
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Poor sleep is linked to consumption of sugary foods/beverages and high neural responsivity to palatable food cues. Yet, whether hedonic liking for sweet taste explains these associations remains unclear. We examined cross-sectional associations of five sleep traits (chronotype, sleep duration, insomnia frequency, snoring, daytime dozing) and a composite sleep score with sweet food liking, and total and free sugar intake in 76,734 UK Biobank participants (39-72 years, 56.3% female). Models adjust...
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BackgroundThe surgical stress response is a predictable, physician-managed metabolic state triggered by anesthesia and tissue injury, marked by insulin resistance and hypercatabolism that create unique nutritional needs unmet by standard, pre-surgical fasting diets. We developed a multi-nutrient medical food to support perioperative metabolic homeostasis and piloted its safety/tolerability and exploratory outcomes. MethodsIn a single-center pilot trial (n=67) of adults undergoing elective abdom...
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The gut microbiota has been implicated in regulating body composition, insulin resistance, and energy metabolism through microbial metabolites, including short-chain fatty acids (SCFAs) and amino acids. However, evidence in adolescents, particularly regarding sex-specific differences and lifestyle such as alcohol intake, remains limited. Characterizing sex-specific metabolic signatures in adolescence may improve early identification of metabolic risk. To address this gap, we investigated associ...
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Sleep architecture is essential for metabolic and cardiovascular health, yet the impact of day-to-day dietary variation on objective sleep physiology remains unclear. Using 4.8 thousand person-nights with real-time dietary logs and multi-stage wearable sleep recordings, we examined how prior-day nutrition relates to next-night sleep under free-living conditions. Higher fiber density was associated with increased restorative sleep, including +0.59 pp deep sleep, +0.76 pp REM sleep, -1.35 pp light...
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ObjectivesNon-communicable diseases (NCDs) account for almost 90% of deaths in Europe, yet comparative estimates of the productivity costs associated with premature NCD mortality across diseases and countries remain limited. This study estimates and compares productivity losses attributable to cardiovascular disease (CVD) and cancer mortality among working-age populations across Europe. Population-based data were used to estimate productivity costs for CVD and cancer deaths across 30 European co...
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BackgroundCaloric restriction (CR) improves markers of biological aging, yet long-term effects on the human metabolome remain unclear. ObjectiveThis study examined the effects of CR (2 years) in healthy adults without obesity on circulating metabolites linked to aging and metabolic adaptations. MethodsUntargeted metabolomics was performed using fasted plasma samples collected at baseline, 12, and 24 months (BL, 12M, 24M) from CALERIE participants randomized to CR or ad libitum (AL) control. A ...
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IntroductionDepression is highly prevalent among young adults worldwide. While research links health behaviours, such as dietary intake, to depression, few studies have examined these associations among young adults in low- and middle-income countries, including South Africa. This study investigated whether dietary intake was associated with an increased risk of depression in a cohort of young South African adults, aged 20-30 years, as part of the Global burden of disease Lifestyle And mental Di...
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Objective To test the effectiveness of a postpartum behavioural intervention delivered by automated text messaging in reducing weight. Design Two parallel group, multicentre, randomised controlled trial. Setting Recruitment from five areas across the United Kingdom (Belfast, Bradford, Stirling, London and Cardiff) through healthcare and community pathways, including social media. Participants A diverse sample of 892 women between 6 weeks and 24 months postpartum, aged 18 years or more and with a...
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BackgroundUniversal Free School Meals (UFSM) were introduced by the Welsh Government in 2022 to provide every primary school child (aged 4-11) with a free meal at lunch time by 2024, aiming to improve nutrition and reduce inequality. While evidence suggests UFSM can support dietary quality and social inclusion; uptake remains inconsistent, and concerns have been raised regarding meal quality and portion sizes. Aims/ObjectivesThis study explored the perceptions of children and parents regarding ...
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BackgroundHuman milk (HM) bioactive components can have immune modulatory functions, impact the gut microbiome, and may result in functional benefits when added to infant formula (IF). In this single-arm, prospective, intervention study, we tested the effectiveness of an IF with a whey protein concentrate co-enriched in -lactalbumin, milk fat globule membrane (MFGM), and Sn-2 palmitate resulting in protein and lipid profiles observed in HM. The outcomes tested were feeding tolerance, Bifidobacte...
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BackgroundOrganization, time management, and planning (OTMP) difficulties are associated with academic underachievement. OTMP skills training programs are effective in reducing OTMP deficits and improving academic performance. A randomized controlled trial of Homework, Organization, and Planning Skills (HOPS) for students ages 11-14 (1) found it to be effective with medium to large effects. In that study, HOPS was provided by counselors employed by the research team. This study is a replication ...